Our work on arginine methylation via PRMT6 in mediating liver cancer stemness is published in this week’s issue of Cell Reports. Read all about it!
Chan LH*, Zhou L*, Ng KY*, Wong TL*, Lee TK, Sharma R, Loong JH, Ching YP, Yuan YF, Xie D, Lo CM, Man K, Artegiani B, Clevers H, Yan HH, Leung SY, Richard S, Guan XY, Huen MS, Ma S. PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation. Cell Rep 2018; 25:690-701. (*equal contribution)
August 26 2018
Translating our knowledge to the public
Our article in Now.com (Life) – 〈好Heal〉拆解癌症迷思
Part of the article shown below.
Full version can be found here.
This year, we welcome Matthew (our new PhD student) as well as Marco and Alan (our BBMS FYP students) to the team. Best of luck with your studies ahead!
August 28 2018 – Theme Based Research Scheme (TBRS) Symposium: Gastric Cancer Genomics and Beyond – Organoids, Genomics and Cell Biology
Stephanie presented the team’s latest work on use of organoids for the studies of gastric and liver cancer biology.
August 14-18 2018 – Cold Spring Harbor Lab Meeting – Mechanisms and Models of Cancer.
Great meeting! Stephanie shared the team’s work ‘Arginine methylation by PRMT6 as a novel stemness and metabolic regulator in hepatocellular carcinoma”. Bonus: meeting James Watson! #watsonandcrick #thedoublehelix #nobellaureate #DNA #90yo
Aug 6-8 2018 – Cancer Stem Cell Conference 2018 in Cleveland, Ohio. This is the third meeting series of this biannual event. Stephanie presented the team’s work on PRMT6 and its effect through post-translational modification via arginine methylation in the context of liver cancer.
Great catching up with Jack our former PhD graduate in NYC! Thanks for coming out all the way from Connecticut. All the best to your research at Yale!