Very happy to see our work on PTK7 as a novel molecular driver in metastatic HCC finally published in Cellular and Molecular Gastroenterology and Hepatology. Congrats to Matthew! Read the article here.
Findings from this study demonstrated PTK7 as a novel regulator of HCC metastasis. Specifically, we found PTK7 to be critical in driving TGF-β signaling activation, induction of metastatic phenotypes, and guiding of specific epithelial-mesenchymal transition (EMT) status.