Our new paper in Cell Reports!

Our work on arginine methylation via PRMT6 in mediating liver cancer stemness is published in this week’s issue of Cell Reports.┬áRead all about it!

Chan LH*, Zhou L*, Ng KY*, Wong TL*, Lee TK, Sharma R, Loong JH, Ching YP, Yuan YF, Xie D, Lo CM, Man K, Artegiani B, Clevers H, Yan HH, Leung SY, Richard S, Guan XY, Huen MS, Ma S. PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation. Cell Rep 2018; 25:690-701. (*equal contribution)

https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31498-0

Our recent work published in Journal of Hepatology

Our work on the role of ANXA3 in sorafenib resistance is now published in the Journal of Hepatology. Congrats to Carol and the team!

Tong M, Che N, Zhou L, Luk ST, Kau PW, Chai S, Ngan ES, Lo CM, Man K, Ding J, Lee TK, Ma S. Efficacy of antibody-mediated annexin A3 blockade in sensitizing hepatocellular carcinoma to sorafenib and regorafenib treatment. J Hepatol 2018; Epub ahead of print.

https://www.journal-of-hepatology.eu/article/S0168-8278(18)32119-6/fulltext